M Anna Kowalska Selected Research

Platelet Factor 4

1/2022	Dose Escalation Trial of Desulfated Heparin (ODSH) in Septic Peritonitis.
1/2020	FcRn augments induction of tissue factor activity by IgG-containing immune complexes.
1/2020	Fc-modified HIT-like monoclonal antibody as a novel treatment for sepsis.
1/2019	Platelet Factor 4 Attenuates Experimental Acute Liver Injury in Mice.
12/2012	Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials.
1/2012	The role of platelet factor 4 in local and remote tissue damage in a mouse model of mesenteric ischemia/reperfusion injury.
9/2011	Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT.
8/2011	The role of platelet factor 4 in radiation-induced thrombocytopenia.
4/2010	Role of the platelet chemokine platelet factor 4 (PF4) in hemostasis and thrombosis.
8/2008	Platelet factor 4 mediates inflammation in experimental cerebral malaria.

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M Anna Kowalska Research Topics

Disease

14	Thrombosis (Thrombus) 01/2018 - 08/2003
8	Thrombocytopenia (Thrombopenia) 01/2020 - 03/2006
8	Hemorrhage 01/2017 - 08/2003
8	Inflammation (Inflammations) 01/2017 - 06/2004
7	Colonic Neoplasms (Colon Cancer) 01/2020 - 01/2016
6	Neoplasms (Cancer) 01/2021 - 12/2004
4	Sepsis (Septicemia) 01/2022 - 09/2007
4	Neoplasm Metastasis (Metastasis) 01/2019 - 12/2004
4	Vascular System Injuries 03/2015 - 06/2004
4	Atherosclerosis 01/2009 - 06/2004
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 10/2017
3	Adenocarcinoma 01/2019 - 10/2017
2	Fibrosis (Cirrhosis) 01/2022 - 04/2010
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2019 - 04/2010
2	Reperfusion Injury 01/2017 - 01/2012
2	Hemophilia A (Haemophilia) 12/2010 - 12/2003
2	Disease Susceptibility (Diathesis) 11/2004 - 08/2003
1	Peritonitis 01/2022
1	Hemolysis 01/2020
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2020
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2020
1	Venous Thromboembolism 01/2020
1	Thromboembolism 01/2020
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2018
1	Carcinoma (Carcinomatosis) 10/2017
1	Acute Lung Injury 02/2017
1	Endotoxemia 01/2017
1	Melanoma (Melanoma, Malignant) 01/2016
1	Malaria 12/2012
1	Mesenteric Ischemia 01/2012
1	Liver Diseases (Liver Disease) 04/2010
1	Septic Shock (Toxic Shock Syndrome) 04/2010
1	Non-alcoholic Fatty Liver Disease 04/2010
1	Neointima 07/2009
1	Cerebral Malaria 08/2008

Drug/Important Bio-Agent (IBA)

14	Platelet Factor 4IBA 01/2022 - 11/2004
10	ChemokinesIBA 01/2020 - 06/2004
9	Proteins (Proteins, Gene)FDA Link 01/2020 - 08/2003
8	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 11/2004
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 11/2016
3	Histones (Histone)IBA 01/2022 - 01/2014
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 09/2014
3	AntibodiesIBA 01/2020 - 03/2006
3	Protein CIBA 01/2017 - 09/2007
3	Hemostatics (Antihemorrhagics)IBA 02/2016 - 08/2003
3	ferric chlorideIBA 12/2010 - 11/2004
2	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2019
2	Monoclonal AntibodiesIBA 01/2020 - 01/2020
2	Messenger RNA (mRNA)IBA 01/2019 - 04/2010
2	Fibrinolytic Agents (Antithrombotic Agents)IBA 02/2016 - 08/2003
2	ProdrugsIBA 02/2016 - 06/2010
2	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 02/2016 - 08/2003
2	Plasminogen Activators (Plasminogen Activator)IBA 02/2016 - 06/2010
2	Thrombin FDA Link 05/2012 - 09/2007
2	FibrinIBA 05/2012 - 12/2004
2	GlycosaminoglycansIBA 09/2011 - 06/2004
2	Factor VIII (Coagulation Factor VIII)IBA 12/2010 - 12/2003
2	LigandsIBA 04/2010 - 12/2004
2	Apolipoproteins E (ApoE)IBA 07/2009 - 11/2007
2	Biological ProductsIBA 09/2007 - 06/2004
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	Deoxyribonuclease I (Nickase)IBA 01/2020
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2020
1	GlypicansIBA 01/2020
1	N,N-di-n-propylserotonin (NDPS)IBA 01/2020
1	Cathepsin BIBA 01/2019
1	Deoxyribonucleases (DNase)FDA Link 01/2018
1	Fibronectins (Fibronectin)IBA 10/2017
1	FilaminsIBA 10/2017
1	TalinIBA 10/2017
1	IntegrinsIBA 10/2017
1	ThrombomodulinIBA 01/2017
1	Single-Chain AntibodiesIBA 01/2017
1	neuromedin UIBA 11/2016
1	Small Leucine-Rich ProteoglycansIBA 01/2016
1	LumicanIBA 01/2016
1	Heparinoids (Heparinoid)IBA 01/2014
1	Thrombopoietin (c-mpl Ligand)IBA 08/2011
1	Thioacetamide (Thioacetamid)IBA 04/2010
1	Transforming Growth Factor beta (TGF-beta)IBA 04/2010
1	Interleukin-10 (Interleukin 10)IBA 04/2010
1	CXC ChemokinesIBA 04/2010
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 04/2010
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 04/2010
1	beta- 1,3- galactosyl- O- glycosyl- glycoprotein beta-1,6-acetylglucosaminyl transferaseIBA 07/2009
1	ApolipoproteinsIBA 07/2009
1	Chemokine CCL5IBA 01/2009
1	Peptides (Polypeptides)IBA 01/2009
1	Met- RANTESIBA 01/2009
1	serglycinIBA 04/2008
1	Proteoglycans (Proteoglycan)IBA 04/2008
1	Blocking AntibodiesIBA 08/2007
1	HirudinsIBA 12/2004
1	P-SelectinIBA 12/2004

Therapy/Procedure

4	Therapeutics 01/2019 - 12/2010
2	Drug Therapy (Chemotherapy) 01/2019 - 08/2007
2	Lasers (Laser) 03/2015 - 12/2010
1	Aftercare (After-Treatment) 08/2007